Spurs visit Stamford Bridge on Saturday lunchtime hoping to halt a dreadful run of four Premier League games without victory by recording their first win at Chelsea in 22 years.
The Blues, meanwhile, are desperate to bounce back from defeat at high-flying Man City and continue their resurgence under Roberto Di Matteo.
Victory for Chelsea would lift them two points behind Spurs in the all important race for a Champions League spot, further denting their North London rivals' diminishing confidence.
Here are the key tussles likely to determine the outcome of this blockbuster fixture...
The midfield battle
Probable starters Frank Lampard, Michael Essien and Ramires should hope to overun Scott Parker and Sandro in midfield, while Spurs are banking for a sprinkling of Luka Modric magic to inflict damage on the team who publicly courted him so desperately last summer. Spurs were criticised for getting outplayed at the Emirates in that (ahem) 5-2 drubbing, placing added emphasis on Harry Redknapp to tactically outmuscle his rookie adversary.
Didier Drogba versus Spurs' back two
With Ledley King doubtful and uncharacteristically out-of-sorts when fit, Didier Drogba is likely to get the nod having sat out at Man City in mid-week and will fancy his chances against either King, veteran Ryan Nelsen or Younes Kaboul. Should Torres continue as Chelsea's lone striker, the Spaniard's new found enthusiasm could frighten the life out of Spurs, as he looks to build on his brace against Leicester.
Louis Saha or Jermain Defoe versus Chelsea's back two
Chelsea captain John Terry is expected to return following a one-game break and should partner curly haired Brazilian David Luiz. They'll fancy their chances of keeping either Louis Saha or Jermain Defoe quiet, owing to Emmanuel Adebayor's hamstring strain.
Gareth Bale against Chelsea's full-backs
Impetus and form favours Chelsea, so Harry and co. will be praying Branislav Ivanovic's thigh problem forces the Blues to start with Jose Bosingwa, providing Gareth Bale with encouragement to wreak havoc. Aaron Lennon is also a major doubt for Spurs, who were banking on his pace to trouble an ageing Chelsea back four.
Chelsea 2-1 Spurs
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