Kevin Pietersen is facing up to eight weeks on the sidelines after being ruled out of the final Test against New Zealand.
The England batsman has been troubled by a knee injury since the start of the three-match series and the England and Wales Cricket Board has confirmed he will play no part in the series decider in Queenstown.
Pietersen, 32, is to return home for further tests and will miss the Indian Premier League, which begins on April 3.
"Pietersen experienced knee pain while fielding in preparation for the four-day game in Queenstown earlier this month, ahead of the Test series. This has failed to resolve satisfactorily," read an ECB statement.
"Recent scans confirm an injury to the right knee with bone bruising and possible cartilage damage to the kneecap. The 32-year-old will return to the UK for further investigations and specialist review.
"The injury is likely to require ongoing assessments and a likely six-eight week period of rest and rehabilitation. Pietersen has therefore been withdrawn from all cricket including the Indian Premier League."